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Amiloride/Hydrochlorothiazide is used for:
Treating fluid retention (edema) and high blood pressure. It may be used alone or with other medicines. It may also be used for other conditions as determined by your doctor.
Amiloride/Hydrochlorothiazide is a diuretic (water pill) and is
a combination of a potassium-sparing diuretic (amiloride) and a thiazide diuretic (hydrochlorothiazide). It works by making the kidneys eliminate sodium (salt) and water from the body, which helps to lower blood pressure. The amiloride component helps minimize potassium loss.
Do NOT use Amiloride/Hydrochlorothiazide if:
you are allergic to any ingredient in Amiloride/Hydrochlorothiazide or any other sulfonamide
you are unable to urinate, have severely decreased kidney function, or high blood potassium
you are taking other potassium-sparing diuretics (eg, spironolactone), potassium supplements, salt substitutes containing potassium, or dofetilide
Contact your doctor or health care provider right away if any of these apply to you.
Before using Amiloride/Hydrochlorothiazide :
Some medical conditions may interact with Amiloride/Hydrochlorothiazide . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have cirrhosis or liver problems, diabetes, gout, kidney problems or kidney stones, asthma, heart problems, or systemic lupus erythematosus
(SLE or lupus)
if you have elevated blood acid, low folic acid levels, or electrolyte problems, or are dehydrated
Some MEDICINES MAY INTERACT with Amiloride/Hydrochlorothiazide . Tell your health care provider if you are taking any other medicines, especially any of the following:
Potassium-sparing diuretics (eg, spironolactone), potassium supplements, or
salt substitutes containing potassium because high blood potassium levels may occur and cause listlessness, confusion, abnormal skin sensations of the arms and legs, heaviness of limbs, slowed heart rate, irregular heart rhythm, or stopping of the heart
Cholestyramine or colestipol because they may decrease Amiloride/Hydrochlorothiazide 's effectiveness
Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin) because they may decrease Amiloride/Hydrochlorothiazide 's effectiveness of Amiloride/Hydrochlorothiazide may be decreased and the risk of kidney problems may be increased
Barbiturates (eg, phenobarbital), certain chemotherapy medicines, corticosteroids
(eg, prednisone), digoxin, dofetilide, ketanserin, narcotic pain medicines (eg, codeine), or medicines for high blood pressure because the risk of their side effects may be increased by Amiloride/Hydrochlorothiazide
Diazoxide, lithium, or nondepolarizing neuromuscular
blockers (eg, pancuronium)
because their actions and the risk of their side effects may be increased by Amiloride/Hydrochlorothiazide
Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) because the risk of high blood potassium and kidney problems may be increased by Amiloride/Hydrochlorothiazide
Diabetes medicines (eg, glipizide) or insulin because their effectiveness may be decreased by Amiloride/Hydrochlorothiazide
This may not be a complete list of all interactions that may occur. Ask your health care provider if Amiloride/Hydrochlorothiazide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Amiloride/Hydrochlorothiazide :
Use Amiloride/Hydrochlorothiazide as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take Amiloride/Hydrochlorothiazide by mouth with food.
Amiloride/Hydrochlorothiazide may increase the amount of urine or cause you to urinate more often when you first
start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
If you miss a dose of Amiloride/Hydrochlorothiazide , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Amiloride/Hydrochlorothiazide .
Important safety information:
Amiloride/Hydrochlorothiazide may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Amiloride/Hydrochlorothiazide with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Amiloride/Hydrochlorothiazide may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
Amiloride/Hydrochlorothiazide may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Amiloride/Hydrochlorothiazide . Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
Tell your doctor or dentist that you take Amiloride/Hydrochlorothiazide before you receive any medical or dental care, emergency care, or surgery.
Diabetes patients - Amiloride/Hydrochlorothiazide may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
Lab tests, including liver function, kidney function, lung function, blood pressure, and fasting blood glucose, may be performed while you use Amiloride/Hydrochlorothiazide . These tests may
be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Amiloride/Hydrochlorothiazide should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Amiloride/Hydrochlorothiazide while you are pregnant. It is not known if Amiloride/Hydrochlorothiazide is found in breast milk. Do not breast-feed while taking Amiloride/Hydrochlorothiazide .
Information on this website is intended to supplement, not be a substitute for, the expertise and judgement of your doctor, pharmacist or other healthcare professional. The sale to you by us of any product should not be construed to indicate that the use of any such product is either safe, unsafe, appropriate, or effective for you or anybody else. You must consult your healthcare professional, doctor or pharmacist if you are unsure about taking, using or giving of a particular medication or product or acting or relying on any information contained in this website. Always read the label of any products purchased